Remove all packing materials before first using. Normal care the mattress by vacuum clean or wiping the mattress surface with a slightly damp cloth, air dry and then put on fitted sheet. It is also good to kill the microbe and germ on mattress under the sun. To clean urine or vomits, use a few drops of white vinegar into mild soap diluted with water and wipe surface with sponge or cloth, wipe again with clean damp cloth until clean. Natural air dry the mattress or with slightly warm temperature. Do not use iron to dry the surface as it will damage the ticking.